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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PXN
All Species:
29.7
Human Site:
S274
Identified Species:
54.44
UniProt:
P49023
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49023
NP_001074324.1
591
64533
S274
D
E
L
M
A
S
L
S
D
F
K
I
Q
D
L
Chimpanzee
Pan troglodytes
XP_001159942
589
64154
S272
D
E
L
M
A
S
L
S
D
F
K
I
Q
G
L
Rhesus Macaque
Macaca mulatta
XP_001085795
563
61555
S280
D
E
L
M
A
S
L
S
D
F
K
F
M
A
Q
Dog
Lupus familis
XP_543425
664
72715
S285
D
E
L
M
A
S
L
S
D
F
K
V
Q
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VI36
591
64458
S274
D
E
L
M
A
S
L
S
D
F
K
M
Q
G
L
Rat
Rattus norvegicus
Q66H76
586
64001
T265
P
S
P
V
P
A
I
T
V
N
Q
G
E
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P49024
559
61224
S275
D
E
L
M
A
S
L
S
D
F
K
F
M
A
Q
Frog
Xenopus laevis
Q2TCH4
506
55983
G235
R
V
P
D
S
V
S
G
S
K
V
P
E
A
T
Zebra Danio
Brachydanio rerio
Q6P7E4
419
45574
H148
K
P
A
L
S
S
P
H
N
G
H
G
V
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523601
581
64668
S262
D
D
L
M
A
S
L
S
D
F
K
V
S
N
G
Honey Bee
Apis mellifera
XP_624308
559
62451
S259
K
A
T
K
S
S
Q
S
P
L
P
S
E
G
T
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
R142
S
D
V
R
S
N
G
R
S
P
S
R
D
P
L
Sea Urchin
Strong. purpuratus
XP_780574
695
76058
S357
D
D
L
M
A
S
L
S
D
F
Q
L
S
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
92.5
83.1
N.A.
93.7
74.9
N.A.
N.A.
84.7
41.2
21.6
N.A.
43.1
43.3
33.8
43.4
Protein Similarity:
100
99.1
92.8
85.2
N.A.
95.7
78.3
N.A.
N.A.
88.4
54.3
36.5
N.A.
54.8
57
47
56.2
P-Site Identity:
100
93.3
73.3
80
N.A.
86.6
0
N.A.
N.A.
73.3
0
6.6
N.A.
66.6
13.3
6.6
60
P-Site Similarity:
100
93.3
73.3
86.6
N.A.
93.3
40
N.A.
N.A.
73.3
13.3
26.6
N.A.
86.6
26.6
33.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
62
8
0
0
0
0
0
0
0
31
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
62
24
0
8
0
0
0
0
62
0
0
0
8
8
0
% D
% Glu:
0
47
0
0
0
0
0
0
0
0
0
0
24
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
62
0
16
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
8
0
8
0
16
0
31
8
% G
% His:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
16
0
0
0
% I
% Lys:
16
0
0
8
0
0
0
0
0
8
54
0
0
0
0
% K
% Leu:
0
0
62
8
0
0
62
0
0
8
0
8
0
0
31
% L
% Met:
0
0
0
62
0
0
0
0
0
0
0
8
16
8
0
% M
% Asn:
0
0
0
0
0
8
0
0
8
8
0
0
0
8
0
% N
% Pro:
8
8
16
0
8
0
8
0
8
8
8
8
0
16
8
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
16
0
31
0
16
% Q
% Arg:
8
0
0
8
0
0
0
8
0
0
0
8
0
0
0
% R
% Ser:
8
8
0
0
31
77
8
70
16
0
8
8
16
0
16
% S
% Thr:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
24
% T
% Val:
0
8
8
8
0
8
0
0
8
0
8
16
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _